Baylor College of Medicine's Human Genome Sequencing Center (HGSC), in
collaboration with DNAnexus, received a Best Practice award this week at
the Bio-IT World Conference and Expo. The award for IT Infrastructure
and High Performance Computing recognized the organizations' work on
processing genomic data for the Cohorts for Heart and Aging Research in
Genomic Epidemiology (CHARGE) Consortium using Baylor's Mercury pipeline.
"This is a great achievement to be recognized at Bio-IT World for the
work we've done with high performance cloud computing. With
DNAnexus' help, we have been able to operate at scale, store immense
amounts of data, work with our collaborators and beat short deadlines
- all of which would have been prohibitively expensive or extremely
challenging to accomplish using local resources," said Narayanan
Veeraraghavan, Lead Programmer Scientist at the Baylor College of
Medicine Human Genome Sequencing Center.
"We are honored to be recognized alongside Baylor's Human Genome
Sequencing Center and proud of our contributions to the CHARGE project,"
said Richard Daly, CEO of DNAnexus. "The DNAnexus platform offers
research and clinical enterprises a proven high-performance computing
infrastructure that allows them to focus on the data and provide the
ability to share andcollaborate in a secure and compliant cloud-based
The HGSC's Mercury pipeline identifies mutations from genomic data,
setting the stage for determining the significance of these mutations as
a cause of serious disease and is used as the core variant-calling
pipeline for the CHARGE Consortium. The CHARGE Consortium is aimed at
better understanding how human genetics contributes to heart disease and
aging. Over the course of a four-week period, approximately 3.3 million
core-hours of computational time were used to analyze more than 14,000
genomes, generating 430TB of results and nearly 1PB of data storage
hosted by DNAnexus for further analysis. This project represented the
largest genomic analysis ever performed in the cloud.
The Best Practices Awards program was established in 2003 by the editors
of Bio-IT World to recognize cutting-edge approaches to the use of
information technology to advance basic biomedical research, drug
discovery, and clinical trials, while providing a blueprint for success
with the potential for impact across the industry. A panel of ten
invited expert judges joined the editors in reviewing 30 detailed
submissions from organizations ranging from large pharmaceutical and
biomedical companies to academic centers to startup service providers
around the world, selecting winners in five categories as well as two
special awards from the judges and the editors.
For more information please visit https://dnanexus.com/usecases-charge.
DNAnexus is powering the genomics revolution with an enterprise-level
solution that combines cloud computing with advanced bioinformatics. The
DNAnexus team is made up of experts in software, computational biology,
and genetics who are on a mission to establish DNAnexus at the center of
a growing ecosystem of scientific and clinical research, and diagnostic
efforts in personalized medicine. For more information please visit https://dnanexus.com.
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